Building Robust Transcriptomes with Master Splicing Factors
نویسندگان
چکیده
Coherent splicing networks arise from many discrete splicing decisions regulated in unison. Here, we examine the properties of robust, context-specific splicing networks. We propose that a subset of key splicing regulators, or "master splicing factors," respond to environmental cues to establish and maintain tissue transcriptomes during development.
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عنوان ژورنال:
- Cell
دوره 159 شماره
صفحات -
تاریخ انتشار 2014